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上海信裕生物科技有限公司
NKRF抗体

NKRF抗体

商家询价

产品名称： NKRF抗体

英文名称： NKRFAntibody

产品编号： XY14693-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 NKRF抗体Applications

In-house applications ELISA, WB, IP     Application not tested? Please see our Guarantee.
Published applications WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Mouse
Images
Prev1NextView more validation data
  • 14693-1-AP;Jurkat cellsJurkat cells were subjected to SDS PAGE followed by western blot with 14693-1-AP(NKRF antibody) at dilution of 1:1000
  • 14693-1-AP;A549 cellsIP Result of anti-NKRF (IP:14693-1-AP, 3ug; Detection:14693-1-AP 1:1000) with A549 cells lysate 1000ug.
Positive WB detected in Jurkat cells, A431 cells, A549 cells, HepG2 cells, PC-3 cells
Positive IP detected in A549 cells
Recommended dilution WB : 1:1000-1:10000
IP : 1:500-1:5000
 NKRF抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information NKRF抗体
Immunogen NKRF fusion protein ag6252 Full name NFKB repressing factor
Calculated molecular
weight		 78 kDa Observed molecular 
weight		 100 kDa
GenBank accession 
number		 BC068514 Gene ID (NCBI) 55922
Gene symbol NKRF Synonyms ITBA4, NF kappa B repressing factor, NKRF, NRF, Protein ITBA4, Transcription factor NRF
Background

NKRF, also named as Protein ITBA4 or Transcription factor NRF, is a 690 amino acid protein, which contains one G-patch domain and one R3H domain. NKRF is Widely and constitutively expressed, with lower level in colon, peripheral blood lymphocytes, lung and kidney. NKRF interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. NKRF is involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. NKRF抗体

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